|Application ||WB, IHC-P|
|Reactivity||Human, Mouse, Rat, Horse, Bovine, Dog|
|Dilution||IHC-P (10 µg/ml), WB (1-2 µg/ml),|
|Other Names||Nucleoporin NUP53, 35 kDa nucleoporin, Mitotic phosphoprotein 44, MP-44, Nuclear pore complex protein Nup53, Nucleoporin Nup35, NUP35, MP44, NUP53|
|Target/Specificity||Human NUP35 / NUP53|
|Reconstitution & Storage||Store at 4°C for short term applications. For long term storage, aliquot and store at -20°C.|
|Precautions||NUP35 / NUP53 Antibody (aa50-100) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs). Can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. May play a role in the association of MAD1 with the NPC.|
|Cellular Location||Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein. Note=Tightly associated with the nuclear membrane and lamina.|
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Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs). Can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. May play a role in the association of MAD1 with the NPC.
Cronshaw J.M.,et al.J. Cell Biol. 158:915-927(2002).
Guo J.H.,et al.Submitted (AUG-2001) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 434:724-731(2005).
Hawryluk-Gara L.A.,et al.Mol. Biol. Cell 16:2382-2394(2005).
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