|Application ||WB, IHC-P, E|
|Reactivity||Human, Mouse, Rat, Rabbit, Monkey, Pig, Chicken, Horse, Xenopus, Bovine, Dog|
|Dilution||ELISA (1:16000), IHC-P (3.75 µg/ml), WB (0.1-0.3 µg/ml)|
|Other Names||Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3, Transducin beta chain 3, GNB3|
|Target/Specificity||Human GNB3. This antibody is expected to recognize GNB3 & GNB4 (GeneID: 2784, 59345; ProteinID: NP_002066.1; NP_067642.1).|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||GNB3 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction.|
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Provided below are standard protocols that you may find useful for product applications.
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction.
Levine M.A.,et al.Proc. Natl. Acad. Sci. U.S.A. 87:2329-2333(1990).
Ansari-Lari M.A.,et al.Genome Res. 6:314-326(1996).
Ansari-Lari M.A.,et al.Genome Res. 7:268-280(1997).
Rosskopf D.,et al.Hypertension 36:33-41(2000).
Puhl H.L. III,et al.Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
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