|Application ||WB, IHC-P, E|
|Reactivity||Human, Rabbit, Horse, Bovine, Dog|
|Dilution||ELISA (1:16000), IHC-P (3.75 µg/ml), WB (0.1-0.3 µg/ml)|
|Other Names||Delta-sarcoglycan, Delta-SG, 35 kDa dystrophin-associated glycoprotein, 35DAG, SGCD|
|Target/Specificity||Human SGCD / Delta-Sarcoglycan. This antibody is expected to recognize isoform 1 (NP_000328.2) and isoform 3 (NP_001121681.1).|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||SGCD / Delta-Sarcoglycan Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.|
|Cellular Location||Cell membrane, sarcolemma; Single-pass type II membrane protein. Cytoplasm, cytoskeleton|
|Tissue Location||Most strongly expressed in skeletal and cardiac muscle. Also detected in smooth muscle. Weak expression in brain and lung|
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Provided below are standard protocols that you may find useful for product applications.
Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
Nigro V.,et al.Hum. Mol. Genet. 5:1179-1186(1996).
Jung D.,et al.J. Biol. Chem. 271:32321-32329(1996).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Moreira E.S.,et al.J. Med. Genet. 35:951-953(1998).
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