|Application ||WB, IHC-P, E|
|Reactivity||Human, Rabbit, Horse, Bovine, Dog|
|Dilution||ELISA (1:16000), IHC-P (3.75 µg/ml), WB (0.1-0.3 µg/ml)|
|Other Names||Delta-sarcoglycan, Delta-SG, 35 kDa dystrophin-associated glycoprotein, 35DAG, SGCD|
|Target/Specificity||Human SGCD / Delta-Sarcoglycan. This antibody is expected to recognize isoform 1 (NP_000328.2) and isoform 3 (NP_001121681.1).|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||SGCD / Delta-Sarcoglycan Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.|
|Cellular Location||Cell membrane, sarcolemma; Single-pass type II membrane protein. Cytoplasm, cytoskeleton|
|Tissue Location||Most strongly expressed in skeletal and cardiac muscle. Also detected in smooth muscle. Weak expression in brain and lung|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
Nigro V.,et al.Hum. Mol. Genet. 5:1179-1186(1996).
Jung D.,et al.J. Biol. Chem. 271:32321-32329(1996).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Moreira E.S.,et al.J. Med. Genet. 35:951-953(1998).
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