AK1 / Adenylate Kinase 1 Antibody (aa101-150)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, IF, E |
---|---|
Primary Accession | P00568 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 22kDa |
Dilution | ELISA (1:5000), IF (1:100-1:500), IHC-P (5 µg/ml) |
Gene ID | 203 |
---|---|
Other Names | Adenylate kinase isoenzyme 1 {ECO:0000255|HAMAP-Rule:MF_03171}, AK 1 {ECO:0000255|HAMAP-Rule:MF_03171}, 2.7.4.3 {ECO:0000255|HAMAP-Rule:MF_03171}, 2.7.4.6 {ECO:0000255|HAMAP-Rule:MF_03171}, ATP-AMP transphosphorylase 1 {ECO:0000255|HAMAP-Rule:MF_03171}, ATP:AMP phosphotransferase {ECO:0000255|HAMAP-Rule:MF_03171}, Adenylate monophosphate kinase {ECO:0000255|HAMAP-Rule:MF_03171}, Myokinase {ECO:0000255|HAMAP-Rule:MF_03171}, AK1 {ECO:0000255|HAMAP-Rule:MF_03171} |
Target/Specificity | KAD1 Antibody detects endogenous levels of total KAD1 protein. |
Reconstitution & Storage | Store at -20°C for up to one year. |
Precautions | AK1 / Adenylate Kinase 1 Antibody (aa101-150) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | AK1 {ECO:0000255|HAMAP-Rule:MF_03171} |
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Function | Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP (PubMed:2542324). Exhibits nucleoside diphosphate kinase activity, catalyzing the production of ATP, CTP, GTP, UTP, dATP, dCTP, dGTP and dTTP from the corresponding diphosphate substrates with either ATP or GTP as phosphate donor (PubMed:23416111). Also catalyzes at a very low rate the synthesis of thiamine triphosphate (ThTP) from thiamine diphosphate (ThDP) and ADP (By similarity). |
Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:P05081}. |
Volume | 50 µl |
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Background
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
References
von Zabern I.,et al.Eur. J. Biochem. 68:281-290(1976).
Matsuura S.,et al.J. Biol. Chem. 264:10148-10155(1989).
Noma T.,et al.Submitted (DEC-1998) to the EMBL/GenBank/DDBJ databases.
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Lubec G.,et al.Submitted (DEC-2008) to UniProtKB.
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