|Application ||WB, IHC-P, E|
|Reactivity||Human, Mouse, Rat|
|Dilution||ELISA (1:1000), IHC-P (5 µg/ml), WB (1:500-1:1000)|
|Other Names||Cell division cycle-associated protein 3, Gene-rich cluster protein C8, Trigger of mitotic entry protein 1, TOME-1, CDCA3, C8, GRCC8, TOME1|
|Target/Specificity||CDCA3 Antibody detects endogenous levels of total CDCA3 protein.|
|Reconstitution & Storage||Store at -20°C for up to one year.|
|Precautions||CDCA3 Antibody (aa219-268) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||C8, GRCC8, TOME1|
|Function||F-box-like protein which is required for entry into mitosis. Acts by participating in E3 ligase complexes that mediate the ubiquitination and degradation of WEE1 kinase at G2/M phase (By similarity).|
|Cellular Location||Cytoplasm, cytosol.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
F-box-like protein which is required for entry into mitosis. Acts by participating in E3 ligase complexes that mediate the ubiquitination and degradation of WEE1 kinase at G2/M phase (By similarity).
Walker M.G.,et al.Curr. Cancer Drug Targets 1:73-83(2001).
Ansari-Lari M.A.,et al.Genome Res. 7:268-280(1997).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Olsen J.V.,et al.Cell 127:635-648(2006).
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