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CTSS / Cathepsin S Antibody
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P |
|---|---|
| Primary Accession | P25774 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 37kDa |
| Dilution | IHC-P (5 µg/ml), WB (0.5-4 µg/ml), |
| Gene ID | 1520 |
|---|---|
| Other Names | Cathepsin S, 3.4.22.27, CTSS |
| Target/Specificity | Detects 37 kD human cathepsin S. Cross-reactivity to other species has not been determined. |
| Reconstitution & Storage | Long term: -70°C; Short term: -20°C |
| Precautions | CTSS / Cathepsin S Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CTSS |
|---|---|
| Function | Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules and MHC class II antigen presentation (PubMed:30612035). The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L. |
| Cellular Location | Lysosome. Secreted. Cytoplasmic vesicle, phagosome |
| Volume | 50 µl |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond- specificity of this proteinase is in part similar to the specificities of cathepsin L and cathepsin N.
References
Shi G.-P.,et al.J. Biol. Chem. 267:7258-7262(1992).
Wiederanders B.,et al.J. Biol. Chem. 267:13708-13713(1992).
Wiederanders B.,et al.Submitted (MAY-1995) to the EMBL/GenBank/DDBJ databases.
Shi G.-P.,et al.J. Biol. Chem. 269:11530-11536(1994).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
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