|Application ||WB, IHC-P, IF, ICC|
|Dilution||IHC-P (5 µg/ml), WB (1-2 µg/ml),|
|Other Names||Septin-1, LARP, Peanut-like protein 3, Serologically defined breast cancer antigen NY-BR-24, SEPT1, DIFF6, PNUTL3|
|Target/Specificity||Human SEPT1 / Septin 1. At least two isoforms of SEPT1 are known to exist. This antibody is predicted to not cross-react with other Septin protein family members.|
|Reconstitution & Storage||Store at -20°C. Aliquot to avoid freeze/thaw cycles.|
|Precautions||SEPT1 / Septin 1 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential).|
|Cellular Location||Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Midbody. Note=Remains at the centrosomes and the nearby microtubules throughout mitosis Localizes to the midbody during cytokinesis|
|Tissue Location||Expressed at high levels in lymphoid and hematopoietic tissues.|
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Provided below are standard protocols that you may find useful for product applications.
Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential).
Tu Q.,et al.Submitted (AUG-1998) to the EMBL/GenBank/DDBJ databases.
Peng J.,et al.Submitted (MAY-2001) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Scanlan M.J.,et al.Cancer Immun. 1:4-4(2001).
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