|Application ||IHC-P, E|
|Dilution||IHC-P (10 µg/ml)|
|Other Names||Tafazzin, Protein G4.5, TAZ, EFE2, G4.5|
|Reconstitution & Storage||Aliquot and freeze at -20° C. Avoid freeze-thaw cycles.|
|Precautions||TAZ Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Some isoforms may be involved in cardiolipin (CL) metabolism.|
|Cellular Location||Isoform 1: Membrane; Single-pass membrane protein Isoform 3: Membrane; Single-pass membrane protein Isoform 5: Membrane; Single-pass membrane protein Isoform 7: Membrane; Single-pass membrane protein Isoform 9: Cytoplasm.|
|Tissue Location||High levels in cardiac and skeletal muscle. Up to 10 isoforms can be present in different amounts in different tissues. Most isoforms are ubiquitous. Isoforms that lack the N- terminus are found in leukocytes and fibroblasts, but not in heart and skeletal muscle. Some forms appear restricted to cardiac and skeletal muscle or to leukocytes|
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Provided below are standard protocols that you may find useful for product applications.
Some isoforms may be involved in cardiolipin (CL) metabolism.
Bione S.,et al.Nat. Genet. 12:385-389(1996).
Lu B.,et al.Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Ross M.T.,et al.Nature 434:325-337(2005).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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