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MYT1 Antibody (aa41-90)

Rabbit Polyclonal Antibody

     
  • IHC - MYT1 Antibody (aa41-90) ALS15747
    Human, Brain, cerebellum: Formalin-Fixed Paraffin-Embedded (FFPE)
    detail
  • WB - MYT1 Antibody (aa41-90) ALS15747
    Western blot of extracts from HUVEC cells, using ZNF387 Antibody.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
  • detail
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q01538
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 122kDa
Dilution ELISA (1:10000), IHC-P (20 µg/ml), WB (1:500-1:1000)
Additional Information
Gene ID 4661
Other Names Myelin transcription factor 1, MyT1, Myelin transcription factor I, MyTI, PLPB1, Proteolipid protein-binding protein, MYT1, KIAA0835, KIAA1050, MTF1, MYTI, PLPB1
Target/Specificity ZNF387 Antibody detects endogenous levels of total ZNF387 protein.
Reconstitution & Storage Store at -20°C for up to one year.
PrecautionsMYT1 Antibody (aa41-90) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MYT1
Synonyms KIAA0835, KIAA1050, MTF1, MYTI, PLPB1
Function Binds to the promoter region of genes encoding proteolipid proteins of the central nervous system. May play a role in the development of neurons and oligodendroglia in the CNS. May regulate a critical transition point in oligodendrocyte lineage development by modulating oligodendrocyte progenitor proliferation relative to terminal differentiation and up-regulation of myelin gene transcription.
Cellular Location Nucleus.
Tissue Location Mostly in developing nervous system. Expressed in neural progenitors and oligodendrocyte lineage cells. More highly expressed in oligodendrocyte progenitors than in differentiated oligodendrocytes.
Volume 50 µl
Research Areas
Citations (0)
citation

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Background

Binds to the promoter regions of proteolipid proteins of the central nervous system. May play a role in the development of neurons and oligodendrogalia in the CNS. May regulate a critical transition point in oligodendrocyte lineage development by modulating oligodendrocyte progenitor proliferation relative to terminal differentiation and up-regulation of myelin gene transcription.

References

Nagase T.,et al.DNA Res. 5:355-364(1998).
Deloukas P.,et al.Nature 414:865-871(2001).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Kikuno R.,et al.DNA Res. 6:197-205(1999).
Kim J.G.,et al.Mol. Cell. Biol. 12:5632-5639(1992).

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Discontinued
Cat# ALS15747
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