NR1I3 / CAR Antibody (aa71-120)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | Q14994 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 40kDa |
Dilution | ELISA (1:20000), IHC-P (20 µg/ml), WB (1:500-1:1000) |
Gene ID | 9970 |
---|---|
Other Names | Nuclear receptor subfamily 1 group I member 3, Constitutive activator of retinoid response, Constitutive active response, Constitutive androstane receptor, CAR, Orphan nuclear receptor MB67, NR1I3, CAR |
Target/Specificity | NR1I3 Antibody detects endogenous levels of total NR1I3 protein. |
Reconstitution & Storage | Store at -20°C for up to one year. |
Precautions | NR1I3 / CAR Antibody (aa71-120) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | NR1I3 |
---|---|
Synonyms | CAR |
Function | Binds and transactivates the retinoic acid response elements that control expression of the retinoic acid receptor beta 2 and alcohol dehydrogenase 3 genes. Transactivates both the phenobarbital responsive element module of the human CYP2B6 gene and the CYP3A4 xenobiotic response element. |
Cellular Location | Nucleus. Cytoplasm. Cytoplasm, cytoskeleton. Note=Recruited to the cytoplasm by DNAJC7. |
Tissue Location | Predominantly expressed in liver. |
Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
Background
Binds and transactivates the retinoic acid response elements that control expression of the retinoic acid receptor beta 2 and alcohol dehydrogenase 3 genes. Transactivates both the phenobarbital responsive element module of the human CYP2B6 gene and the CYP3A4 xenobiotic response element.
References
Baes M.,et al.Mol. Cell. Biol. 14:1544-1552(1994).
Lamba J.K.,et al.J. Pharmacol. Exp. Ther. 311:811-821(2004).
Zhou G.,et al.Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
Kaighin V.A.,et al.Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases.
Gregory S.G.,et al.Nature 441:315-321(2006).
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