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ORC3L / ORC3 Antibody (C-Terminus)

Goat Polyclonal Antibody

     
  • IHC - ORC3L / ORC3 Antibody (C-Terminus) ALS15770
    Human Brain, Cortex
  • WB - ORC3L / ORC3 Antibody (C-Terminus) ALS15770
    Antibody (2 ug/ml) staining of HeLa lysate (RIPA buffer, 1.4E5 cells per lane).
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q9UBD5
Reactivity Human, Mouse, Rat, Rabbit, Zebrafish, Hamster, Monkey, Pig, Chicken, Horse, Xenopus, Bovine, Dog
Host Goat
Clonality Polyclonal
Calculated MW 82kDa
Dilution ELISA (1:32000), IHC-P (3.75 µg/ml), WB (1-3 µg/ml)
Additional Information
Gene ID 23595
Other Names Origin recognition complex subunit 3, Origin recognition complex subunit Latheo, ORC3, LATHEO, ORC3L
Target/Specificity Human ORC3 / ORC3L. This antibody is expected to recognize both reported isoforms (NP_862820.1 and NP_036513.2).
Reconstitution & Storage Store at -20°C. Minimize freezing and thawing.
PrecautionsORC3L / ORC3 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ORC3
Synonyms LATHEO, ORC3L
Function Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre- replication complex necessary to initiate DNA replication. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3.
Cellular Location Nucleus.
Citations (0)

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Background

Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre- replication complex necessary to initiate DNA replication. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3.

References

Tugal T.,et al.Submitted (MAR-1999) to the EMBL/GenBank/DDBJ databases.
Dean F.B.,et al.Submitted (FEB-1999) to the EMBL/GenBank/DDBJ databases.
Pinto S.,et al.Neuron 23:45-54(1999).
Wiemann S.,et al.Genome Res. 11:422-435(2001).
Suzuki Y.,et al.Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.

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$ 395.00
Cat# ALS15770
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