|Application ||WB, IHC-P, E|
|Dilution||IHC-P (3.75 µg/ml), WB (1-3 µg/ml),|
|Other Names||Krueppel-like factor 8, Basic krueppel-like factor 3, Zinc finger protein 741, KLF8, BKLF3, ZNF741|
|Target/Specificity||Human KLF8. This antibody is expected to recognise isoform 1 (NP_009181.2) and isoform 2 (NP_001152768.1).|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||KLF8 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Transcriptional repressor and activator. Binds to CACCC- boxes promoter elements. Also binds the GT-box of cyclin D1 promoter and mediates cell cycle progression at G(1) phase as a downstream target of focal adhesion kinase (FAK).|
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Provided below are standard protocols that you may find useful for product applications.
Transcriptional repressor and activator. Binds to CACCC- boxes promoter elements. Also binds the GT-box of cyclin D1 promoter and mediates cell cycle progression at G(1) phase as a downstream target of focal adhesion kinase (FAK).
Gorski J.L.,et al.Submitted (JUN-1995) to the EMBL/GenBank/DDBJ databases.
Camacho-Vanegas O.,et al.FASEB J. 27:432-436(2013).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Totoki Y.,et al.Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
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