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KLF8 Antibody (N-Terminus)
Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | O95600 |
| Reactivity | Human |
| Host | Goat |
| Clonality | Polyclonal |
| Calculated MW | 39kDa |
| Dilution | IHC-P (3.75 µg/ml), WB (1-3 µg/ml), |
| Gene ID | 11279 |
|---|---|
| Other Names | Krueppel-like factor 8, Basic krueppel-like factor 3, Zinc finger protein 741, KLF8, BKLF3, ZNF741 |
| Target/Specificity | Human KLF8. This antibody is expected to recognise isoform 1 (NP_009181.2) and isoform 2 (NP_001152768.1). |
| Reconstitution & Storage | Store at -20°C. Minimize freezing and thawing. |
| Precautions | KLF8 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | KLF8 |
|---|---|
| Synonyms | BKLF3, ZNF741 |
| Function | Transcriptional repressor and activator. Binds to CACCC-boxes promoter elements. Also binds the GT-box of cyclin D1 promoter and mediates cell cycle progression at G(1) phase as a downstream target of focal adhesion kinase (FAK). |
| Cellular Location | Nucleus. |
| Tissue Location | Ubiquitous.. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Transcriptional repressor and activator. Binds to CACCC- boxes promoter elements. Also binds the GT-box of cyclin D1 promoter and mediates cell cycle progression at G(1) phase as a downstream target of focal adhesion kinase (FAK).
References
Gorski J.L.,et al.Submitted (JUN-1995) to the EMBL/GenBank/DDBJ databases.
Camacho-Vanegas O.,et al.FASEB J. 27:432-436(2013).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Totoki Y.,et al.Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
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