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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   ANP32B / APRIL Antibody (C-Terminus)   

ANP32B / APRIL Antibody (C-Terminus)

Goat Polyclonal Antibody

     
  • IHC - ANP32B / APRIL Antibody (C-Terminus) ALS15773
    Anti-ANP32B / APRIL antibody IHC staining of human breast.
  • SPECIFICATION
  • CITATIONS
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  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q92688
Reactivity Human, Mouse, Rat, Pig, Horse, Bovine, Dog
Host Goat
Clonality Polyclonal
Calculated MW 29kDa
Dilution ELISA (1:1000), IHC-P (3.75 µg/ml), WB (0.3-1 µg/ml)
Additional Information
Gene ID 10541
Other Names Acidic leucine-rich nuclear phosphoprotein 32 family member B, Acidic protein rich in leucines, Putative HLA-DR-associated protein I-2, PHAPI2, Silver-stainable protein SSP29, ANP32B, APRIL, PHAPI2
Target/Specificity Human ANP32B / APRIL. This antibody does NOT recognize the TNF family member also known as APRIL - Gene ID number 8741.
Reconstitution & Storage Store at -20°C. Minimize freezing and thawing.
PrecautionsANP32B / APRIL Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ANP32B
Synonyms APRIL, PHAPI2
Function Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. Required for the progression from the G1 to the S phase. Anti-apoptotic protein which functions as a caspase-3 inhibitor. Has no phosphatase 2A (PP2A) inhibitor activity (By similarity). Exhibits histone chaperone properties, stimulating core histones to assemble into a nucleosome.
Cellular Location Isoform 1: Nucleus. Note=Accumulates in the nuclei at the S phase.
Tissue Location Expressed in heart, lung, pancreas, prostate and in spleen, thymus and placenta.
Research Areas
Citations (0)

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Background

Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. Required for the progression from the G1 to the S phase. Anti-apoptotic protein which functions as a caspase-3 inhibitor. Has no phosphatase 2A (PP2A) inhibitor activity (By similarity). Exhibits histone chaperone properties, stimulating core histones to assemble into a nucleosome.

References

Vaesen M.,et al.Submitted (AUG-1996) to the EMBL/GenBank/DDBJ databases.
Zhu L.,et al.Submitted (DEC-1996) to the EMBL/GenBank/DDBJ databases.
Mencinger M.,et al.Biochim. Biophys. Acta 1395:176-180(1998).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Humphray S.J.,et al.Nature 429:369-374(2004).

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$ 395.00
Cat# ALS15773
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