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>   home   >   Products   >   Primary Antibodies   >   Antibody Collections   >   GPCR Antibodies   >   ADRB2 Antibody (aa336-385)   

ADRB2 Antibody (aa336-385)

Rabbit Polyclonal Antibody

     
  • IHC - ADRB2 Antibody (aa336-385) ALS15806
    Anti-ADRB2 antibody IHC staining of human heart.
  • IF - ADRB2 Antibody (aa336-385) ALS15806
    Immunofluorescence of COS7 cells, using ADRB2 Antibody.
  • WB - ADRB2 Antibody (aa336-385) ALS15806
    Western blot of extracts from HepG2 cells, using ADRB2 Antibody.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E
Primary Accession P07550
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 46kDa
Dilution ELISA (1:10000), IF (1:100-1:500), IHC-P (20 µg/ml), WB (1:500-1:1000) ,
Additional Information
Gene ID 154
Other Names Beta-2 adrenergic receptor, Beta-2 adrenoreceptor, Beta-2 adrenoceptor, ADRB2, ADRB2R, B2AR
Target/Specificity ADRB2 Antibody detects endogenous levels of total ADRB2 protein.
Reconstitution & Storage Store at -20°C for up to one year.
PrecautionsADRB2 Antibody (aa336-385) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ADRB2
Synonyms ADRB2R, B2AR
Function Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine.
Cellular Location Cell membrane; Multi- pass membrane protein. Early endosome. Note=Colocalizes with VHL at the cell membrane (PubMed:19584355). Activated receptors are internalized into endosomes prior to their degradation in lysosomes (PubMed:20559325).
Volume 50 µl
Research Areas
Citations (0)

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Background

Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine.

References

Chung F.-Z.,et al.FEBS Lett. 211:200-206(1987).
Kobilka B.K.,et al.J. Biol. Chem. 262:7321-7327(1987).
Schofield P.R.,et al.Nucleic Acids Res. 15:3636-3636(1987).
Kobilka B.K.,et al.Proc. Natl. Acad. Sci. U.S.A. 84:46-50(1987).
Emorine L.J.,et al.Proc. Natl. Acad. Sci. U.S.A. 84:6995-6999(1987).

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$ 395.00
Cat# ALS15806
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