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CHRM4 / M4 Antibody (aa236-285)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, IF, E |
|---|---|
| Primary Accession | P08173 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 53kDa |
| Dilution | ELISA (1:10000), IF (1:100-1:500), IHC-P (20 µg/ml) |
| Gene ID | 1132 |
|---|---|
| Other Names | Muscarinic acetylcholine receptor M4, CHRM4 |
| Target/Specificity | CHRM4 Antibody detects endogenous levels of total CHRM4 protein. |
| Format | PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol |
| Reconstitution & Storage | Store at -20°C for up to one year. |
| Precautions | CHRM4 / M4 Antibody (aa236-285) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CHRM4 |
|---|---|
| Function | The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is inhibition of adenylate cyclase. |
| Cellular Location | Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane; Multi-pass membrane protein |
| Volume | Array |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is inhibition of adenylate cyclase.
References
Bonner T.I.,et al.Science 237:527-532(1987).
Bonner T.I.,et al.Neuron 1:403-410(1988).
Peralta E.G.,et al.EMBO J. 6:3923-3929(1987).
Puhl H.L. III,et al.Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases.
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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