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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   RILPL1 Antibody (N-Terminus)   

RILPL1 Antibody (N-Terminus)

Rabbit Polyclonal Antibody

     
  • IHC - RILPL1 Antibody (N-Terminus) ALS15875
    Anti-RILPL1 antibody IHC staining of human small intestine.
  • IF - RILPL1 Antibody (N-Terminus) ALS15875
    Immunofluorescence of RILPL1 in mouse brain cells with RILPL1 antibody at 20 µg/mL.
  • WB - RILPL1 Antibody (N-Terminus) ALS15875
    Western blot of RILPL1 in rat cerebellum tissue lysate with RILPL1 antibody at (A) 0.5 and (B) 1...
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E
Primary Accession Q5EBL4
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 47kDa
Dilution IF (20 µg/ml), IHC-P (5 µg/ml), WB (0.5-1 µg/ml)
Additional Information
Gene ID 353116
Other Names RILP-like protein 1, Rab-interacting lysosomal-like protein 1, RILPL1, RLP1
Target/Specificity Human RILPL1. At least three isoforms of RILPL1 are known to exist; this antibody will detect the two shorter isoforms. RILPL1 antibody is predicted to not cross-react with RILP.
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
PrecautionsRILPL1 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RILPL1
Synonyms RLP1
Function Plays a role in the regulation of cell shape and polarity. Plays a role in cellular protein transport, including protein transport away from primary cilia. Neuroprotective protein, which acts by sequestring GAPDH in the cytosol and prevent the apoptotic function of GAPDH in the nucleus. Competes with SIAH1 for binding GAPDH (By similarity). Does not regulate lysosomal morphology and distribution.
Cellular Location Cytoplasm, cytosol. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell projection, cilium
Tissue Location Widely expressed. Expressed at lower level in liver and kidney.
Research Areas
Citations (0)

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Background

Plays a role in the regulation of cell shape and polarity. Plays a role in cellular protein transport, including protein transport away from primary cilia. Neuroprotective protein, which acts by sequestring GAPDH in the cytosol and prevent the apoptotic function of GAPDH in the nucleus. Competes with SIAH1 for binding GAPDH (By similarity). Does not regulate lysosomal morphology and distribution.

References

Ota T.,et al.Nat. Genet. 36:40-45(2004).
Scherer S.E.,et al.Nature 440:346-351(2006).
Wang T.,et al.Mol. Biol. Cell 15:815-826(2004).
Dephoure N.,et al.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Burkard T.R.,et al.BMC Syst. Biol. 5:17-17(2011).

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$ 395.00
Cat# ALS15875
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