|Application ||WB, IHC-P, IF, ICC, E|
|Dilution||ICC (2.5 µg/ml), IF (5 µg/ml), IHC-P (2.5 µg/ml), WB (0.25 µg/ml) ,|
|Other Names||Lamina-associated polypeptide 2, isoform alpha, Thymopoietin isoform alpha, TP alpha, Thymopoietin-related peptide isoform alpha, TPRP isoform alpha, Thymopoietin, TP, Splenin, Thymopentin, TP5, TMPO, LAP2|
|Target/Specificity||Human TMPO / Thymopoietin. At least three isoforms of Thymopoietin are known to exist; this antibody will detect all isoforms. Thymopoietin antibody is predicted to not cross-react with other LEM domain-containing proteins.|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.|
|Precautions||TMPO / TP / Thymopoietin Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May be involved in the structural organization of the nucleus and in the post-mitotic nuclear assembly. Plays an important role, together with LMNA, in the nuclear anchorage of RB1.|
|Cellular Location||Nucleus. Chromosome. Note=Expressed diffusely throughout the nucleus|
|Tissue Location||Expressed in many tissues. Most abundant in adult thymus and fetal liver|
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May be involved in the structural organization of the nucleus and in the post-mitotic nuclear assembly. Plays an important role, together with LMNA, in the nuclear anchorage of RB1.
Harris C.A.,et al.Proc. Natl. Acad. Sci. U.S.A. 91:6283-6287(1994).
Harris C.A.,et al.Genomics 28:198-205(1995).
Hara H.,et al.Biochem. Mol. Biol. Int. 34:927-933(1994).
Bienvenut W.V.,et al.Submitted (MAR-2008) to UniProtKB.
Audhya T.,et al.Proc. Natl. Acad. Sci. U.S.A. 84:3545-3549(1987).
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