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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   SLC35D2 Antibody (C-Terminus)   

SLC35D2 Antibody (C-Terminus)

Rabbit Polyclonal Antibody

     
  • ICC - SLC35D2 Antibody (C-Terminus) ALS15890
    Immunocytochemistry of SLC35D2 in HeLa cells with SLC35D2 antibody at 5 µg/mL.
  • IHC - SLC35D2 Antibody (C-Terminus) ALS15890
    Anti-SLC35D2 antibody IHC staining of human small intestine.
  • WB - SLC35D2 Antibody (C-Terminus) ALS15890
    Western blot analysis of SLC35D2 in HeLa cell lysate with SLC35D2 antibody at (A) 1 and (B) 2 ug/ml.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, ICC, E
Primary Accession Q76EJ3
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 37kDa
Dilution ICC (5 µg/ml), IHC-P (5 µg/ml), WB (1-2 µg/ml)
Additional Information
Gene ID 11046
Other Names UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter, Homolog of Fringe connection protein 1, HFRC1, SQV7-like protein, SQV7L, Solute carrier family 35 member D2, UDP-galactose transporter-related protein 8, UGTrel8, SLC35D2, HFRC, UGTREL8
Target/Specificity Human SLC35D2. At least two isoforms of SLC35D2 are known to exist; this antibody will recognize both isoforms. SLC35D2 antibody is predicted to not cross-react with SLC35D1 or SLC35D3.
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
PrecautionsSLC35D2 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SLC35D2
Synonyms HFRC, UGTREL8
Function Antiporter transporting nucleotide sugars such as UDP-N- acetylglucosamine (UDP-GlcNAc), UDP-glucose (UDP-Glc) and GDP- mannose (GDP-Man) pooled in the cytosol into the lumen of the Golgi in exchange for the corresponding nucleosides monophosphates (UMP for UDP-sugars and GMP for GDP-sugars). May take part in heparan sulfate synthesis by supplying UDP-Glc-NAc, the donor substrate, and thus be involved in growth factor signaling.
Cellular Location Golgi apparatus membrane; Multi- pass membrane protein
Tissue Location Highly expressed in heart, kidney, small intestine, placenta, lung and peripheral blood leukocyte. Weakly expressed in skeletal muscle and spleen. Not expressed in brain, colon and thymus.
Research Areas
Citations (0)

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Background

Antiporter transporting nucleotide sugars such as UDP-N- acetylglucosamine (UDP-GlcNAc), UDP-glucose (UDP-Glc) and GDP- mannose (GDP-Man) pooled in the cytosol into the lumen of the Golgi in exchange for the corresponding nucleosides monophosphates (UMP for UDP-sugars and GMP for GDP-sugars). May take part in heparan sulfate synthesis by supplying UDP-Glc-NAc, the donor substrate, and thus be involved in growth factor signaling.

References

Suda T.,et al.J. Biol. Chem. 279:26469-26474(2004).
Ishida N.,et al.Genomics 85:106-116(2005).
Humphray S.J.,et al.Nature 429:369-374(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Herman T.,et al.Proc. Natl. Acad. Sci. U.S.A. 96:974-979(1999).

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$ 395.00
Cat# ALS15890
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