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SDHAF2 Antibody (N-Terminus)
Chicken Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | Q9NX18 |
| Reactivity | Human, Mouse, Rat |
| Host | Chicken |
| Clonality | Polyclonal |
| Calculated MW | 20kDa |
| Dilution | IHC-P (5 µg/ml), WB (1 µg/ml), |
| Gene ID | 54949 |
|---|---|
| Other Names | Succinate dehydrogenase assembly factor 2, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03057}, SDH assembly factor 2 {ECO:0000255|HAMAP-Rule:MF_03057}, SDHAF2 {ECO:0000255|HAMAP-Rule:MF_03057}, SDHAF2 {ECO:0000255|HAMAP-Rule:MF_03057} |
| Target/Specificity | Human SDHAF2. SDHAF2 antibody is predicted to not cross-react with other SDHAF protein family members. |
| Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted. |
| Precautions | SDHAF2 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SDHAF2 {ECO:0000255|HAMAP-Rule:MF_03057} |
|---|---|
| Function | Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer. |
| Cellular Location | Mitochondrion matrix {ECO:0000255|HAMAP- Rule:MF_03057, ECO:0000269|PubMed:19628817} |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer.
References
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hao H.-X.,et al.Science 325:1139-1142(2009).
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