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SDHAF2 Antibody (N-Terminus)

Chicken Polyclonal Antibody

     
  • IHC - SDHAF2 Antibody (N-Terminus) ALS15891
    Anti-SDHAF2 antibody IHC staining of human small intestine.
  • SPECIFICATION
  • CITATIONS
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  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q9NX18
Reactivity Human, Mouse, Rat
Host Chicken
Clonality Polyclonal
Calculated MW 20kDa
Dilution IHC-P (5 µg/ml), WB (1 µg/ml),
Additional Information
Gene ID 54949
Other Names Succinate dehydrogenase assembly factor 2, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03057}, SDH assembly factor 2 {ECO:0000255|HAMAP-Rule:MF_03057}, SDHAF2 {ECO:0000255|HAMAP-Rule:MF_03057}, SDHAF2 {ECO:0000255|HAMAP-Rule:MF_03057}
Target/Specificity Human SDHAF2. SDHAF2 antibody is predicted to not cross-react with other SDHAF protein family members.
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
PrecautionsSDHAF2 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SDHAF2 {ECO:0000255|HAMAP-Rule:MF_03057}
Function Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer.
Cellular Location Mitochondrion matrix {ECO:0000255|HAMAP- Rule:MF_03057, ECO:0000269|PubMed:19628817}
Citations (0)

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Background

Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer.

References

Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hao H.-X.,et al.Science 325:1139-1142(2009).

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$ 395.00
Cat# ALS15891
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