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Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | P06865 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | AT20F1 |
| Calculated MW | 61kDa |
| Dilution | IHC-P (10 µg/ml), WB (1:3000), |
| Gene ID | 3073 |
|---|---|
| Other Names | Beta-hexosaminidase subunit alpha, 3.2.1.52, Beta-N-acetylhexosaminidase subunit alpha, Hexosaminidase subunit A, N-acetyl-beta-glucosaminidase subunit alpha, HEXA |
| Target/Specificity | Human HEXA |
| Reconstitution & Storage | Can be stored at 4°C. For long term storage, aliquot and store at -20°C. Avoid repeated freezing and thawing cycles. |
| Precautions | HEXA Antibody (clone AT20F1) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | HEXA |
|---|---|
| Function | Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues. The form B is active against certain oligosaccharides. The form S has no measurable activity. |
| Cellular Location | Lysosome. |
| Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
Background
Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues. The form B is active against certain oligosaccharides. The form S has no measurable activity.
References
Myerowitz R.,et al.Proc. Natl. Acad. Sci. U.S.A. 82:7830-7834(1985).
Proia R.L.,et al.J. Biol. Chem. 262:5677-5681(1987).
Triggs-Raine B.L.,et al.Am. J. Hum. Genet. 49:1041-1054(1991).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Suzuki Y.,et al.Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
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