|Application ||WB, IHC-P, E|
|Dilution||IHC-P (10 µg/ml), WB (1:3000),|
|Other Names||Beta-hexosaminidase subunit alpha, 220.127.116.11, Beta-N-acetylhexosaminidase subunit alpha, Hexosaminidase subunit A, N-acetyl-beta-glucosaminidase subunit alpha, HEXA|
|Reconstitution & Storage||Can be stored at 4°C. For long term storage, aliquot and store at -20°C. Avoid repeated freezing and thawing cycles.|
|Precautions||HEXA Antibody (clone AT20F1) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues. The form B is active against certain oligosaccharides. The form S has no measurable activity.|
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Provided below are standard protocols that you may find useful for product applications.
Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues. The form B is active against certain oligosaccharides. The form S has no measurable activity.
Myerowitz R.,et al.Proc. Natl. Acad. Sci. U.S.A. 82:7830-7834(1985).
Proia R.L.,et al.J. Biol. Chem. 262:5677-5681(1987).
Triggs-Raine B.L.,et al.Am. J. Hum. Genet. 49:1041-1054(1991).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Suzuki Y.,et al.Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
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