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HEXA Antibody (clone AT20F1)

Mouse Monoclonal Antibody

     
  • WB - HEXA Antibody (clone AT20F1) ALS15896
    Western Blot: The cell lysates of MCF7 (40 ug) were resolved by SDS-PAGE, transferred to PVDF...
  • IHC - HEXA Antibody (clone AT20F1) ALS15896
    Anti-HEXA antibody IHC staining of human lung.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P06865
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names AT20F1
Calculated MW 61kDa
Dilution IHC-P (10 µg/ml), WB (1:3000),
Additional Information
Gene ID 3073
Other Names Beta-hexosaminidase subunit alpha, 3.2.1.52, Beta-N-acetylhexosaminidase subunit alpha, Hexosaminidase subunit A, N-acetyl-beta-glucosaminidase subunit alpha, HEXA
Target/Specificity Human HEXA
Reconstitution & Storage Can be stored at 4°C. For long term storage, aliquot and store at -20°C. Avoid repeated freezing and thawing cycles.
PrecautionsHEXA Antibody (clone AT20F1) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HEXA
Function Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues. The form B is active against certain oligosaccharides. The form S has no measurable activity.
Cellular Location Lysosome.
Volume 50 µl
Research Areas
Citations (0)

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Background

Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues. The form B is active against certain oligosaccharides. The form S has no measurable activity.

References

Myerowitz R.,et al.Proc. Natl. Acad. Sci. U.S.A. 82:7830-7834(1985).
Proia R.L.,et al.J. Biol. Chem. 262:5677-5681(1987).
Triggs-Raine B.L.,et al.Am. J. Hum. Genet. 49:1041-1054(1991).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Suzuki Y.,et al.Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.

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$ 395.00
Cat# ALS15896
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