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>   home   >   Products   >   Primary Antibodies   >   Cardiovascular   >   APOOL / Apolipoprotein O-Like Antibody (aa219-268)   

APOOL / Apolipoprotein O-Like Antibody (aa219-268)

Rabbit Polyclonal Antibody

     
  • WB - APOOL / Apolipoprotein O-Like Antibody (aa219-268) ALS15907
    Western blot of extracts from COLO/NIH-3T3 cells, using APOOL Antibody.
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q6UXV4
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 29kDa
Dilution ELISA (1:40000), IHC-P (10 µg/ml), WB (1:500-1:1000)
Additional Information
Gene ID 139322
Other Names MICOS complex subunit MIC27, Apolipoprotein O-like, Protein FAM121A, APOOL, CXorf33, FAM121A, MIC27
Target/Specificity APOOL Antibody detects endogenous levels of total APOOL protein.
Reconstitution & Storage Store at -20°C for up to one year.
PrecautionsAPOOL / Apolipoprotein O-Like Antibody (aa219-268) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name APOOL
Synonyms CXorf33, FAM121A, MIC27
Function Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Specifically binds to cardiolipin (in vitro) but not to the precursor lipid phosphatidylglycerol. Plays a crucial role in crista junction formation and mitochondrial function (PubMed:23704930), (PubMed:25764979).
Cellular Location Mitochondrion inner membrane; Multi- pass membrane protein. Mitochondrion
Volume 50 µl
Research Areas
Citations (0)

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Background

Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Specifically binds to cardiolipin (in vitro) but not to the precursor lipid phosphatidylglycerol.

References

Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Ross M.T.,et al.Nature 434:325-337(2005).
Burkard T.R.,et al.BMC Syst. Biol. 5:17-17(2011).
Weber T.A.,et al.PLoS ONE 8:E63683-E63683(2013).
Pfanner N.,et al.J. Cell Biol. 204:1083-1086(2014).

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$ 395.00
Cat# ALS15907
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