|Application ||WB, IHC-P, E|
|Dilution||ELISA (1:20000-1:80000), IHC-P (5 µg/ml), WB (1:1000-1:2000)|
|Other Names||F-box/WD repeat-containing protein 4, Dactylin, F-box and WD-40 domain-containing protein 4, FBXW4, FBW4, SHFM3|
|Target/Specificity||Human SHFM3 / FBXW4.|
|Reconstitution & Storage||Store at -20°C for up to one year.|
|Precautions||SHFM3 / FBXW4 Antibody (aa5-186) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. Likely to be involved in key signaling pathways crucial for normal limb development. May participate in Wnt signaling.|
|Tissue Location||Expressed in brain, kidney, lung and liver.|
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Provided below are standard protocols that you may find useful for product applications.
Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. Likely to be involved in key signaling pathways crucial for normal limb development. May participate in Wnt signaling.
Ianakiev P.,et al.Biochem. Biophys. Res. Commun. 261:64-70(1999).
Ilyin G.P.,et al.Genomics 67:40-47(2000).
Deloukas P.,et al.Nature 429:375-381(2004).
de Mollerat X.J.,et al.Hum. Mol. Genet. 12:1959-1971(2003).
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