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SERPINE1 / PAI-1 Antibody (clone 1D5)

Mouse Monoclonal Antibody

     
  • IHC - SERPINE1 / PAI-1 Antibody (clone 1D5) ALS15927
    Anti-SERPINE1 / PAI-1 antibody IHC staining of human prostate.
  • WB - SERPINE1 / PAI-1 Antibody (clone 1D5) ALS15927
    Western blot using SERPINE1 monoclonal antibody against HEK293 (1) and SERPINE1 (AA:...
  • SPECIFICATION
  • CITATIONS
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  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC, E, Flo
Primary Accession P05121
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 1D5
Calculated MW 45kDa
Dilution ELISA (1:10000), Flo (1:200-1:400), IHC (10 µg/ml), WB (1:500-1:2000) ,
Additional Information
Gene ID 5054
Other Names Plasminogen activator inhibitor 1, PAI, PAI-1, Endothelial plasminogen activator inhibitor, Serpin E1, SERPINE1, PAI1, PLANH1
Target/Specificity Human SERPINE1 / PAI-1
Reconstitution & Storage Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles.
PrecautionsSERPINE1 / PAI-1 Antibody (clone 1D5) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SERPINE1
Synonyms PAI1, PLANH1
Function Serine protease inhibitor. This inhibitor acts as 'bait' for tissue plasminogen activator, urokinase, protein C and matriptase-3/TMPRSS7. Its rapid interaction with PLAT may function as a major control point in the regulation of fibrinolysis.
Cellular Location Secreted.
Tissue Location Found in plasma and platelets and in endothelial, hepatoma and fibrosarcoma cells
Research Areas
Citations (0)

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Background

Serine protease inhibitor. This inhibitor acts as 'bait' for tissue plasminogen activator, urokinase, protein C and matriptase-3/TMPRSS7. Its rapid interaction with PLAT may function as a major control point in the regulation of fibrinolysis.

References

Pannekoek H.,et al.EMBO J. 5:2539-2544(1986).
Loskutoff D.J.,et al.Biochemistry 26:3763-3768(1987).
Ginsburg D.,et al.J. Clin. Invest. 78:1673-1680(1986).
Follo M.,et al.Gene 84:447-453(1989).
Strandberg L.,et al.Eur. J. Biochem. 176:609-616(1988).

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$ 395.00
Cat# ALS15927
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