|Application ||WB, IHC-P, E|
|Reactivity||Human, Mouse, Rat|
|Dilution||ELISA (1:40000), IHC-P (10 µg/ml), WB (1:500-1:1000)|
|Other Names||Nuclear envelope pore membrane protein POM 121, Nuclear envelope pore membrane protein POM 121A, Nucleoporin Nup121, Pore membrane protein of 121 kDa, POM121, KIAA0618, NUP121, POM121A|
|Target/Specificity||POM121 Antibody detects endogenous levels of total POM121 protein.|
|Reconstitution & Storage||Store at -20°C for up to one year.|
|Precautions||POM121 Antibody (aa1197-1246) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||KIAA0618, NUP121, POM121A|
|Function||Essential component of the nuclear pore complex (NPC). The repeat-containing domain may be involved in anchoring components of the pore complex to the pore membrane. When overexpressed in cells induces the formation of cytoplasmic annulate lamellae (AL).|
|Cellular Location||Nucleus, nuclear pore complex. Nucleus membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein Note=Stably associated with the NPC throughout interphase and the endoplasmic reticulum during metaphase.|
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Provided below are standard protocols that you may find useful for product applications.
Essential component of the nuclear pore complex (NPC). The repeat-containing domain may be involved in anchoring components of the pore complex to the pore membrane. When overexpressed in cells induces the formation of cytoplasmic annulate lamellae (AL).
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Ohara O.,et al.Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 424:157-164(2003).
Funakoshi T.,et al.FEBS Lett. 581:4910-4916(2007).
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