|Application ||WB, IHC-P, E|
|Reactivity||Human, Mouse, Rat|
|Dilution||ELISA (1:40000), IHC-P (10 µg/ml), WB (1:500-1:1000)|
|Other Names||Nuclear envelope pore membrane protein POM 121, Nuclear envelope pore membrane protein POM 121A, Nucleoporin Nup121, Pore membrane protein of 121 kDa, POM121, KIAA0618, NUP121, POM121A|
|Target/Specificity||POM121 Antibody detects endogenous levels of total POM121 protein.|
|Reconstitution & Storage||Store at -20°C for up to one year.|
|Precautions||POM121 Antibody (aa1197-1246) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||KIAA0618, NUP121, POM121A|
|Function||Essential component of the nuclear pore complex (NPC). The repeat-containing domain may be involved in anchoring components of the pore complex to the pore membrane. When overexpressed in cells induces the formation of cytoplasmic annulate lamellae (AL).|
|Cellular Location||Nucleus, nuclear pore complex. Nucleus membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein Note=Stably associated with the NPC throughout interphase and the endoplasmic reticulum during metaphase.|
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Provided below are standard protocols that you may find useful for product applications.
Essential component of the nuclear pore complex (NPC). The repeat-containing domain may be involved in anchoring components of the pore complex to the pore membrane. When overexpressed in cells induces the formation of cytoplasmic annulate lamellae (AL).
Ishikawa K.,et al.DNA Res. 5:169-176(1998).
Ohara O.,et al.Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 424:157-164(2003).
Funakoshi T.,et al.FEBS Lett. 581:4910-4916(2007).
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