|Application ||WB, IHC-P, E|
|Reactivity||Human, Mouse, Rat|
|Dilution||ELISA (1:40000), IHC-P (10 µg/ml), WB (1:500-1:1000)|
|Other Names||Ras-related protein Rab-6C, Rab6-like protein WTH3, RAB6C, WTH3|
|Target/Specificity||RAB6C Antibody detects endogenous levels of total RAB6C protein.|
|Reconstitution & Storage||Store at -20°C for up to one year.|
|Precautions||RAB6C Antibody (aa165-214) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May be involved in the regulation of centrosome duplication and cell cycle progression.|
|Cellular Location||Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome|
|Tissue Location||Highest levels are found in fetal and adult brain, prostate, testis and spinal cord. Undetectable expression in adrenal gland, skeletal muscle, bone marrow, fetal, and adult liver, heart, salivary gland, and trachea. Detected in the HEK293, HEK293T, LNCaP, MCF-7, T-47D and EVSA-T cell lines (at protein level).|
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May be involved in the regulation of centrosome duplication and cell cycle progression.
Shan J.,et al.Biochim. Biophys. Acta 1589:112-123(2002).
Wiemann S.,et al.Genome Res. 11:422-435(2001).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Hillier L.W.,et al.Nature 434:724-731(2005).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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