|Application ||WB, IHC-P, IF, Flo|
|Dilution||Flo (1:100), IF (1:100), IHC-P (20 µg/ml), WB (1:2000) ,|
|Other Names||Microtubule-associated protein RP/EB family member 2, APC-binding protein EB2, End-binding protein 2, EB2, MAPRE2, RP1|
|Target/Specificity||Human MAPRE2 / EB2|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||MAPRE2 / EB2 Antibody (clone 1F3) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May be involved in microtubule polymerization, and spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration (By similarity).|
|Cellular Location||Cytoplasm, cytoskeleton. Note=Associated with the microtubule network. Accumulates at the plus end of microtubules|
|Tissue Location||Expressed in different tumor cell lines. Up- regulated in activated B- and T-lymphocytes|
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May be involved in microtubule polymerization, and spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration (By similarity).
Renner C.,et al.J. Immunol. 159:1276-1283(1997).
Oishi N.,et al.Submitted (AUG-1998) to the EMBL/GenBank/DDBJ databases.
Halleck A.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Kalnine N.,et al.Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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