|Application ||WB, IF, ICC, E, IHC-Fr, Flo|
|Reactivity||Human, Mouse, Rat, Rabbit, Zebrafish, Sheep, Bovine, Dog|
|Dilution||Flo (1:100-1:200), ICC (1:100-1:200), IHC-Fr (1:50), WB (1:100-1:1000) ,|
|Other Names||Lamin-B1, LMNB1, LMN2, LMNB|
|Target/Specificity||Reacts with an epitope located C-terminal of residue 231 in lamin B1.|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.|
|Precautions||LMNB1 / Lamin B1 Antibody (clone 119D5-F1) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin.|
|Cellular Location||Nucleus inner membrane; Lipid-anchor; Nucleoplasmic side|
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Provided below are standard protocols that you may find useful for product applications.
Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin.
Pollard K.M.,et al.Mol. Cell. Biol. 10:2164-2175(1990).
Lin F.,et al.Genomics 27:230-236(1995).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Bienvenut W.V.,et al.Submitted (DEC-2008) to UniProtKB.
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