|Application ||WB, IHC-P, E|
|Dilution||IHC-P (10 µg/ml), WB (1-2 µg/ml),|
|Other Names||MICOS complex subunit MIC25, Coiled-coil-helix cristae morphology protein 1, Coiled-coil-helix-coiled-coil-helix domain-containing protein 6, CHCHD6, CHCM1, MIC25|
|Target/Specificity||CHCHD6 is predicted to not cross-react to other members of the CHCHD family.|
|Reconstitution & Storage||Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.|
|Precautions||CHCHD6 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.|
|Cellular Location||Mitochondrion inner membrane; Lipid-anchor. Mitochondrion|
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Provided below are standard protocols that you may find useful for product applications.
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
An J.,et al.J. Biol. Chem. 287:7411-7426(2012).
Muzny D.M.,et al.Nature 440:1194-1198(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Xie J.,et al.FEBS Lett. 581:3545-3549(2007).
Dephoure N.,et al.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
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