|Application ||WB, IHC-P, IF, E|
|Reactivity||Human, Mouse, Rat|
|Dilution||IF (20 µg/ml), IHC-P (10 µg/ml), WB (1-2 µg/ml)|
|Other Names||Progesterone-induced-blocking factor 1, PIBF1, C13orf24, PIBF|
|Target/Specificity||Multiple isoforms of PIBF1 exists as a result of alternative splicing event.|
|Reconstitution & Storage||Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.|
|Precautions||PIBF1 / PIBF Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Mediator of progesterone that by acting on the phospholipase A2 enzyme interferes with arachidonic acid metabolism, induces a Th2 biased immune response, and by controlling NK activity exerts an anti-abortive effect.|
|Tissue Location||Expressed at highest levels in testis. Moderate expression is detected in spleen, thymus, prostate, ovary, small intestine, and colon.|
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Provided below are standard protocols that you may find useful for product applications.
Mediator of progesterone that by acting on the phospholipase A2 enzyme interferes with arachidonic acid metabolism, induces a Th2 biased immune response, and by controlling NK activity exerts an anti-abortive effect.
Rozenblum E.,et al.Hum. Genet. 110:111-121(2002).
Lachmann M.,et al.Int. J. Cancer 112:51-60(2004).
Szekeres-Bartho J.,et al.Submitted (NOV-1997) to the EMBL/GenBank/DDBJ databases.
Dunham A.,et al.Nature 428:522-528(2004).
Szekeres-Bartho J.,et al.Int. Immunopharmacol. 1:1037-1048(2001).
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