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NUCB2 / Nucleobindin 2 Antibody (Internal)

Rabbit Polyclonal Antibody

     
  • WB - NUCB2 / Nucleobindin 2 Antibody (Internal) ALS16014
    Western blot analysis of Nucleobindin-2 in rat brain tissue lysate with Nucleobindin-2 antibody...
    detail
  • IF - NUCB2 / Nucleobindin 2 Antibody (Internal) ALS16014
    Immunofluorescence of Nucleobindin-2 in rat brain tissue with Nucleobindin-2 antibody at 20 ug/ml.
    detail
  • SPECIFICATION
  • CITATIONS: 1
  • PROTOCOLS
  • BACKGROUND
  • detail
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E
Primary Accession P80303
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 50kDa
Dilution IF (20 µg/ml), IHC-P (10 µg/ml), WB (0.5-1 µg/ml)
Additional Information
Gene ID 4925
Other Names Nucleobindin-2, DNA-binding protein NEFA, Gastric cancer antigen Zg4, Prepronesfatin, Nesfatin-1, NUCB2, NEFA
Target/Specificity Nucleobindin-2 antibody is predicted to not cross-react with NUCB1.
Reconstitution & Storage Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
PrecautionsNUCB2 / Nucleobindin 2 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NUCB2 (HGNC:8044)
Synonyms NEFA
Function Calcium-binding protein which may have a role in calcium homeostasis (By similarity). Acts as a non-receptor guanine nucleotide exchange factor which binds to and activates guanine nucleotide-binding protein (G-protein) alpha subunit GNAI3 (By similarity).
Cellular Location Golgi apparatus. Membrane; Peripheral membrane protein. Cytoplasm Secreted. Endoplasmic reticulum. Nucleus envelope. Note=Golgi retention is mediated by its N-terminal region
Tissue Location Predominantly expressed in spleen, testis and normal stomach.
Research Areas
Citations ( 0 )

Background

Calcium-binding protein. May have a role in calcium homeostasis.

References

Barnikol-Watanabe S.,et al.Biol. Chem. Hoppe-Seyler 375:497-512(1994).
Deangelis M.M.,et al.Biochim. Biophys. Acta 1407:84-91(1998).
Line A.,et al.Br. J. Cancer 86:1824-1830(2002).
Yamada M.,et al.Endocrinology 151:2494-2503(2010).
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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Discontinued
Cat# ALS16014
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