NUCB2 / Nucleobindin 2 Antibody (Internal)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS: 1
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, IF, E |
---|---|
Primary Accession | P80303 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 50kDa |
Dilution | IF (20 µg/ml), IHC-P (10 µg/ml), WB (0.5-1 µg/ml) |
Gene ID | 4925 |
---|---|
Other Names | Nucleobindin-2, DNA-binding protein NEFA, Gastric cancer antigen Zg4, Prepronesfatin, Nesfatin-1, NUCB2, NEFA |
Target/Specificity | Nucleobindin-2 antibody is predicted to not cross-react with NUCB1. |
Reconstitution & Storage | Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles. |
Precautions | NUCB2 / Nucleobindin 2 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | NUCB2 (HGNC:8044) |
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Synonyms | NEFA |
Function | Calcium-binding protein which may have a role in calcium homeostasis (By similarity). Acts as a non-receptor guanine nucleotide exchange factor which binds to and activates guanine nucleotide-binding protein (G-protein) alpha subunit GNAI3 (By similarity). |
Cellular Location | Golgi apparatus. Membrane; Peripheral membrane protein. Cytoplasm Secreted. Endoplasmic reticulum. Nucleus envelope. Note=Golgi retention is mediated by its N-terminal region |
Tissue Location | Predominantly expressed in spleen, testis and normal stomach. |
Provided below are standard protocols that you may find useful for product applications.
Background
Calcium-binding protein. May have a role in calcium homeostasis.
References
Barnikol-Watanabe S.,et al.Biol. Chem. Hoppe-Seyler 375:497-512(1994).
Deangelis M.M.,et al.Biochim. Biophys. Acta 1407:84-91(1998).
Line A.,et al.Br. J. Cancer 86:1824-1830(2002).
Yamada M.,et al.Endocrinology 151:2494-2503(2010).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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