|Application ||WB, IHC-P, E|
|Dilution||IHC-P (10 µg/ml), WB (1 µg/ml),|
|Other Names||Transcription termination factor 2, mitochondrial, Mitochondrial transcription termination factor 2, mTERF2, mTERFL, Mitochondrial transcription termination factor-like protein, mTERF domain-containing protein 3, mitochondrial, MTERF2, MTERFD3|
|Target/Specificity||MTERFD3 antibody is predicted to not cross-react with other MTERFD protein family members.|
|Reconstitution & Storage||Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.|
|Precautions||MTERF2 / MTERFD3 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Binds promoter DNA and regulates mitochondrial transcription. Required for normal levels of transcription, both for mRNA and tRNA. Required for normal mitochondrial protein synthesis, assembly of respiratory complexes and normal mitochondrial function (By similarity).|
|Cellular Location||Mitochondrion. Mitochondrion matrix, mitochondrion nucleoid|
|Tissue Location||Expressed in skeletal muscle, heart, liver and pancreas.|
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Provided below are standard protocols that you may find useful for product applications.
Binds promoter DNA and regulates mitochondrial transcription. Required for normal levels of transcription, both for mRNA and tRNA. Required for normal mitochondrial protein synthesis, assembly of respiratory complexes and normal mitochondrial function (By similarity).
Chen Y.,et al.Biochem. Biophys. Res. Commun. 337:1112-1118(2005).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Suzuki Y.,et al.Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Scherer S.E.,et al.Nature 440:346-351(2006).
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