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TMEM135 Antibody (C-Terminus)

Rabbit Polyclonal Antibody

     
  • WB - TMEM135 Antibody (C-Terminus) ALS16017
    Western blot analysis of TMEM135 in rat liver tissue lysate with TMEM135 antibody at (A) 1 and...
    detail
  • IF - TMEM135 Antibody (C-Terminus) ALS16017
    Immunofluorescence of TMEM135 in human liver tissue with TMEM135 antibody at 20 ug/ml.
    detail
  • IHC - TMEM135 Antibody (C-Terminus) ALS16017
    Anti-TMEM135 antibody IHC staining of human liver.
    detail
  • SPECIFICATION
  • CITATIONS
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  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E
Primary Accession Q86UB9
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 52kDa
Dilution IF (20 µg/ml), IHC-P (10 µg/ml), WB (1-2 µg/ml)
Additional Information
Gene ID 65084
Other Names Transmembrane protein 135, Peroxisomal membrane protein 52, PMP52, TMEM135
Target/Specificity At least two isoforms of TMEM135 are known to exist; this antibody will detect both isoforms.
Reconstitution & Storage Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
PrecautionsTMEM135 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TMEM135 (HGNC:26167)
Function Involved in mitochondrial metabolism by regulating the balance between mitochondrial fusion and fission. May act as a regulator of mitochondrial fission that promotes DNM1L-dependent fission through activation of DNM1L. May be involved in peroxisome organization.
Cellular Location Mitochondrion membrane {ECO:0000250|UniProtKB:Q9CYV5}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q9CYV5}. Peroxisome membrane {ECO:0000250|UniProtKB:Q9CYV5}; Multi-pass membrane protein
Research Areas
Citations (0)
citation

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Background

May be involved in peroxisome organization.

References

Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Taylor T.D.,et al.Nature 440:497-500(2006).
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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Discontinued
Cat# ALS16017
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