TMEM135 Antibody (C-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, IF, E |
---|---|
Primary Accession | Q86UB9 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 52kDa |
Dilution | IF (20 µg/ml), IHC-P (10 µg/ml), WB (1-2 µg/ml) |
Gene ID | 65084 |
---|---|
Other Names | Transmembrane protein 135, Peroxisomal membrane protein 52, PMP52, TMEM135 |
Target/Specificity | At least two isoforms of TMEM135 are known to exist; this antibody will detect both isoforms. |
Reconstitution & Storage | Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles. |
Precautions | TMEM135 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | TMEM135 (HGNC:26167) |
---|---|
Function | Involved in mitochondrial metabolism by regulating the balance between mitochondrial fusion and fission. May act as a regulator of mitochondrial fission that promotes DNM1L-dependent fission through activation of DNM1L. May be involved in peroxisome organization. |
Cellular Location | Mitochondrion membrane {ECO:0000250|UniProtKB:Q9CYV5}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q9CYV5}. Peroxisome membrane {ECO:0000250|UniProtKB:Q9CYV5}; Multi-pass membrane protein |
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Provided below are standard protocols that you may find useful for product applications.
Background
May be involved in peroxisome organization.
References
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Taylor T.D.,et al.Nature 440:497-500(2006).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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