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PPFIA3 Antibody (C-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | O75145 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 133kDa |
| Dilution | IHC-P (10 µg/ml), WB (1-2 µg/ml), |
| Gene ID | 8541 |
|---|---|
| Other Names | Liprin-alpha-3, Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3, PTPRF-interacting protein alpha-3, PPFIA3, KIAA0654 |
| Target/Specificity | PPFIA3 antibody is human, mouse, and rat reactive. |
| Reconstitution & Storage | Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles. |
| Precautions | PPFIA3 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PPFIA3 |
|---|---|
| Synonyms | KIAA0654 |
| Function | May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates. |
| Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:Q91Z79}. Cytoplasmic vesicle, secretory vesicle, acrosome. Note=Also detected in epididymosome {ECO:0000250|UniProtKB:Q91Z79} |
| Tissue Location | Predominantly expressed in brain (PubMed:9624153). Also detected in sperm (at protein level) (PubMed:23124857) |
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Provided below are standard protocols that you may find useful for product applications.
Background
May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates.
References
Ishikawa K.,et al.DNA Res. 5:169-176(1998).
Nakajima D.,et al.DNA Res. 9:99-106(2002).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Serra-Pages C.,et al.J. Biol. Chem. 273:15611-15620(1998).
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