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XPNPEP1 / Aminopeptidase P Antibody (C-Terminus)
Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | Q9NQW7 |
| Reactivity | Human, Monkey, Pig, Dog |
| Host | Goat |
| Clonality | Polyclonal |
| Calculated MW | 70kDa |
| Dilution | ELISA (1:32000), IHC-P (5 µg/ml), WB (0.3-1 µg/ml) |
| Gene ID | 7511 |
|---|---|
| Other Names | Xaa-Pro aminopeptidase 1, 3.4.11.9, Aminoacylproline aminopeptidase, Cytosolic aminopeptidase P, Soluble aminopeptidase P, sAmp, X-Pro aminopeptidase 1, X-prolyl aminopeptidase 1, soluble, XPNPEP1 {ECO:0000312|EMBL:AAH05126.1} |
| Target/Specificity | Human XPNPEP1. This antibody is expected to recognize isoform 1 and 2 (NP_065116.2; NP_001161076.1). |
| Reconstitution & Storage | Store at -20°C. Minimize freezing and thawing. |
| Precautions | XPNPEP1 / Aminopeptidase P Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | XPNPEP1 {ECO:0000303|PubMed:10871044, ECO:0000312|HGNC:HGNC:12822} |
|---|---|
| Function | Metalloaminopeptidase that catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Arg- Pro-Pro (PubMed:11106490, PubMed:35165443, PubMed:18515364). Contributes to the degradation of bradykinin (PubMed:11106490). |
| Cellular Location | Cytoplasm, cytosol. |
| Tissue Location | Expressed in all tissues tested, including pancreas, heart, muscle, kidney, liver, lung and brain. Highest levels in pancreas. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Contributes to the degradation of bradykinin. Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Arg-Pro-Pro.
References
Vanhoof G.,et al.Cytogenet. Cell Genet. 78:275-280(1997).
Sprinkle T.J.,et al.Arch. Biochem. Biophys. 378:51-56(2000).
Cottrell G.S.,et al.Biochemistry 39:15121-15128(2000).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
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