INA / Alpha Internexin Antibody
Chicken Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, IF, ICC |
---|---|
Primary Accession | Q16352 |
Reactivity | Human |
Host | Chicken |
Clonality | Polyclonal |
Calculated MW | 55kDa |
Dilution | ICC (1:1000), IF (1:1000), IHC-P (1:500), WB (1:10000) , |
Gene ID | 9118 |
---|---|
Other Names | Alpha-internexin, Alpha-Inx, 66 kDa neurofilament protein, NF-66, Neurofilament-66, Neurofilament 5, INA, NEF5 |
Reconstitution & Storage | +4°C or -20°C, Avoid repeated freezing and thawing. |
Precautions | INA / Alpha Internexin Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | INA |
---|---|
Synonyms | NEF5 |
Function | Class-IV neuronal intermediate filament that is able to self- assemble. It is involved in the morphogenesis of neurons. It may form an independent structural network without the involvement of other neurofilaments or it may cooperate with NEFL to form the filamentous backbone to which NEFM and NEFH attach to form the cross-bridges. May also cooperate with the neuronal intermediate filament protein PRPH to form filamentous networks (By similarity). |
Tissue Location | Found predominantly in adult CNS. |
Volume | 50 µl |
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Background
Class-IV neuronal intermediate filament that is able to self-assemble. It is involved in the morphogenesis of neurons. It may form an independent structural network without the involvement of other neurofilaments or it may cooperate with NF-L to form the filamentous backbone to which NF-M and NF-H attach to form the cross-bridges.
References
Chan S.-O.,et al.Brain Res. Mol. Brain Res. 29:177-184(1995).
Deloukas P.,et al.Nature 429:375-381(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Lubec G.,et al.Submitted (DEC-2008) to UniProtKB.
Matsuoka S.,et al.Science 316:1160-1166(2007).
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