|Application ||WB, IHC-P, IF, ICC|
|Reactivity||Human, Mouse, Rat, Pig, Bovine|
|Dilution||ICC (1:2000), IF (1:2000), IHC-P (1:50), WB (1:10000) ,|
|Other Names||Lysosome-associated membrane glycoprotein 1, LAMP-1, Lysosome-associated membrane protein 1, CD107 antigen-like family member A, CD107a, LAMP1|
|Reconstitution & Storage||+4°C or -20°C, Avoid repeated freezing and thawing.|
|Precautions||LAMP1 / CD107a Antibody (clone 6E2) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis.|
|Cellular Location||Cell membrane; Single-pass type I membrane protein. Endosome membrane; Single-pass type I membrane protein Lysosome membrane; Single-pass type I membrane protein. Late endosome. Note=This protein shuttles between lysosomes, endosomes, and the plasma membrane. Colocalizes with OSBPL1A at the late endosome|
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Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis.
Fukuda M.,et al.J. Biol. Chem. 263:18920-18928(1988).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Dunham A.,et al.Nature 428:522-528(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Mane S.M.,et al.Arch. Biochem. Biophys. 268:360-378(1989).
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