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TXNDC11 Antibody (Internal)
Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | Q6PKC3 |
| Reactivity | Human |
| Host | Goat |
| Clonality | Polyclonal |
| Calculated MW | 111kDa |
| Dilution | ELISA (1:16000), IHC-P (5 µg/ml), WB (1-3 µg/ml) |
| Gene ID | 51061 |
|---|---|
| Other Names | Thioredoxin domain-containing protein 11, EF-hand-binding protein 1, TXNDC11, EFP1 |
| Target/Specificity | Human TXNDC11. |
| Reconstitution & Storage | Store at -20°C. Minimize freezing and thawing. |
| Precautions | TXNDC11 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TXNDC11 |
|---|---|
| Synonyms | EFP1 |
| Function | May act as a redox regulator involved in DUOX proteins folding. The interaction with DUOX1 and DUOX2 suggest that it belongs to a multiprotein complex constituting the thyroid H(2)O(2) generating system. It is however not sufficient to assist DUOX1 and DUOX2 in H(2)O(2) generation. |
| Cellular Location | Endoplasmic reticulum membrane; Single-pass membrane protein |
| Tissue Location | Widely expressed at low level. Expressed at higher level in thyroid and prostate. |
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Provided below are standard protocols that you may find useful for product applications.
Background
May act as a redox regulator involved in DUOX proteins folding. The interaction with DUOX1 and DUOX2 suggest that it belongs to a multiprotein complex constituting the thyroid H(2)O(2) generating system. It is however not sufficient to assist DUOX1 and DUOX2 in H(2)O(2) generation.
References
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mei G.,et al.Submitted (FEB-1999) to the EMBL/GenBank/DDBJ databases.
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Wang D.,et al.J. Biol. Chem. 280:3096-3103(2005).
Tang L.-Y.,et al.Mol. Cell. Proteomics 6:1952-1967(2007).
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