|Application ||WB, IHC-P, E|
|Dilution||ELISA (1:16000), IHC-P (5 µg/ml), WB (1-3 µg/ml)|
|Other Names||Thioredoxin domain-containing protein 11, EF-hand-binding protein 1, TXNDC11, EFP1|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||TXNDC11 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May act as a redox regulator involved in DUOX proteins folding. The interaction with DUOX1 and DUOX2 suggest that it belongs to a multiprotein complex constituting the thyroid H(2)O(2) generating system. It is however not sufficient to assist DUOX1 and DUOX2 in H(2)O(2) generation.|
|Cellular Location||Endoplasmic reticulum membrane; Single-pass membrane protein|
|Tissue Location||Widely expressed at low level. Expressed at higher level in thyroid and prostate|
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Provided below are standard protocols that you may find useful for product applications.
May act as a redox regulator involved in DUOX proteins folding. The interaction with DUOX1 and DUOX2 suggest that it belongs to a multiprotein complex constituting the thyroid H(2)O(2) generating system. It is however not sufficient to assist DUOX1 and DUOX2 in H(2)O(2) generation.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mei G.,et al.Submitted (FEB-1999) to the EMBL/GenBank/DDBJ databases.
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Wang D.,et al.J. Biol. Chem. 280:3096-3103(2005).
Tang L.-Y.,et al.Mol. Cell. Proteomics 6:1952-1967(2007).
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