|Application ||WB, IHC-P, E|
|Reactivity||Human, Rabbit, Monkey, Pig, Horse, Bovine, Guinea Pig|
|Dilution||ELISA (1:128000), IHC-P (5 µg/ml), WB (0.1-0.3 µg/ml)|
|Other Names||Eukaryotic translation elongation factor 1 epsilon-1, Aminoacyl tRNA synthetase complex-interacting multifunctional protein 3, Elongation factor p18, Multisynthase complex auxiliary component p18, EEF1E1, AIMP3, P18|
|Target/Specificity||Human EEF1E1 / AIMP3 / p18. This antibody is expected to recognize both reported isoforms (NP_004271.1; NP_001129122.1).|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||EEF1E1 / AIMP3 Antibody (aa17-29) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Positive modulator of ATM response to DNA damage.|
|Cellular Location||Cytoplasm. Nucleus. Note=Cytoplasmic under growth arrest conditions. Translocated into the nucleus when growth resumes (S phase) and following DNA damage|
|Tissue Location||Down-regulated in various cancer tissues.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Positive modulator of ATM response to DNA damage.
Motegi H.,et al.Submitted (FEB-1998) to the EMBL/GenBank/DDBJ databases.
Mao M.,et al.Proc. Natl. Acad. Sci. U.S.A. 95:8175-8180(1998).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Mungall A.J.,et al.Nature 425:805-811(2003).
Bienvenut W.V.,et al.Submitted (DEC-2008) to UniProtKB.
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