|Application ||WB, IHC-P, E|
|Reactivity||Human, Rabbit, Monkey, Pig, Bovine|
|Dilution||ELISA (1:128000), IHC-P (5 µg/ml), WB (0.1-0.3 µg/ml)|
|Other Names||Disintegrin and metalloproteinase domain-containing protein 19, ADAM 19, 3.4.24.-, Meltrin-beta, Metalloprotease and disintegrin dendritic antigen marker, MADDAM, ADAM19, MLTNB|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||ADAM19 Antibody (aa574-588) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Participates in the proteolytic processing of beta-type neuregulin isoforms which are involved in neurogenesis and synaptogenesis, suggesting a regulatory role in glial cell. Also cleaves alpha-2 macroglobulin. May be involved in osteoblast differentiation and/or osteoblast activity in bone (By similarity).|
|Cellular Location||Membrane; Single-pass type I membrane protein|
|Tissue Location||Expressed in many normal organ tissues and several cancer cell lines|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Participates in the proteolytic processing of beta-type neuregulin isoforms which are involved in neurogenesis and synaptogenesis, suggesting a regulatory role in glial cell. Also cleaves alpha-2 macroglobulin. May be involved in osteoblast differentiation and/or osteoblast activity in bone (By similarity).
Wang Y.-G.,et al.Submitted (DEC-2000) to the EMBL/GenBank/DDBJ databases.
Fritsche J.,et al.Blood 96:732-739(2000).
Wei P.,et al.Biochem. Biophys. Res. Commun. 280:744-755(2001).
Schmutz J.,et al.Nature 431:268-274(2004).
Xu R.,et al.Submitted (MAR-1999) to the EMBL/GenBank/DDBJ databases.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.