|Application ||WB, IHC-P, E|
|Reactivity||Human, Mouse, Rat, Rabbit, Monkey, Pig, Chicken, Horse, Bovine|
|Dilution||ELISA (1:64000), IHC-P (5 µg/ml), WB (1-3 µg/ml)|
|Other Names||Heterogeneous nuclear ribonucleoproteins A2/B1, hnRNP A2/B1, HNRNPA2B1, HNRPA2B1|
|Target/Specificity||Human HNRNPA2B1. This antibody is expected to recognize both reported isoforms (NP_002128.1; NP_112533.1).|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||HNRNPA2B1 Antibody (aa127-137) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved with pre-mRNA processing. Forms complexes (ribonucleosomes) with at least 20 other different hnRNP and heterogeneous nuclear RNA in the nucleus.|
|Cellular Location||Nucleus, nucleoplasm. Cytoplasm. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Component of ribonucleosomes. Predominantly nucleoplasmic, however isoform A2 is also found in the cytoplasm of cells in some tissues. Not found in the nucleolus|
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Provided below are standard protocols that you may find useful for product applications.
Involved with pre-mRNA processing. Forms complexes (ribonucleosomes) with at least 20 other different hnRNP and heterogeneous nuclear RNA in the nucleus.
Burd C.G.,et al.Proc. Natl. Acad. Sci. U.S.A. 86:9788-9792(1989).
Biamonti G.,et al.Nucleic Acids Res. 22:1996-2002(1994).
Kozu T.,et al.Genomics 25:365-371(1995).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Bienvenut W.V.,et al.Submitted (JUN-2009) to UniProtKB.
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