|Application ||WB, IHC-P, E|
|Dilution||IHC-P (10 µg/ml)|
|Other Names||Thiopurine S-methyltransferase, 220.127.116.11, Thiopurine methyltransferase, TPMT|
|Reconstitution & Storage||Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.|
|Precautions||TPMT Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the S-methylation of thiopurine drugs such as 6-mercaptopurine.|
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Provided below are standard protocols that you may find useful for product applications.
Catalyzes the S-methylation of thiopurine drugs such as 6-mercaptopurine.
Honchel R.,et al.Mol. Pharmacol. 43:878-887(1993).
Lee D.,et al.Drug Metab. Dispos. 23:398-405(1995).
Szumlanski C.,et al.DNA Cell Biol. 15:17-30(1996).
Krynetski E.Y.,et al.Pharm. Res. 14:1672-1678(1997).
Otterness D.,et al.Clin. Pharmacol. Ther. 62:60-73(1997).
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