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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   DCXR Antibody (aa182-244)   

DCXR Antibody (aa182-244)

Rabbit Polyclonal Antibody

     
  • WB - DCXR Antibody (aa182-244) ALS16198
    Sample (30 ug of whole cell lysate). A: Hep G2 . 12% SDS PAGE. DCXR antibody diluted at 1:1000.
  • IHC - DCXR Antibody (aa182-244) ALS16198
    Anti-DCXR antibody IHC staining of human kidney.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P
Primary Accession Q7Z4W1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 26kDa
Dilution IHC-P (7.5 µg/ml), WB (1:500-1:3000),
Additional Information
Gene ID 51181
Other Names L-xylulose reductase, XR, 1.1.1.10, Carbonyl reductase II, Dicarbonyl/L-xylulose reductase, Kidney dicarbonyl reductase, kiDCR, Short chain dehydrogenase/reductase family 20C member 1, Sperm surface protein P34H, DCXR, SDR20C1
Target/Specificity Human DCXR
Reconstitution & Storage Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
PrecautionsDCXR Antibody (aa182-244) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DCXR
Synonyms SDR20C1
Function Catalyzes the NADPH-dependent reduction of several pentoses, tetroses, trioses, alpha-dicarbonyl compounds and L- xylulose. Participates in the uronate cycle of glucose metabolism. May play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing xylitol, an osmolyte, thereby preventing osmolytic stress from occurring in the renal tubules.
Cellular Location Membrane; Peripheral membrane protein. Note=Probably recruited to membranes via an interaction with phosphatidylinositol.
Tissue Location Highly expressed in kidney, liver and epididymis. In the epididymis, it is mainly expressed in the proximal and distal sections of the corpus region. Weakly or not expressed in brain, lung, heart, spleen and testis
Volume 50 µl
Research Areas
Citations (0)

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Background

Catalyzes the NADPH-dependent reduction of several pentoses, tetroses, trioses, alpha-dicarbonyl compounds and L- xylulose. Participates in the uronate cycle of glucose metabolism. May play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing xylitol, an osmolyte, thereby preventing osmolytic stress from occurring in the renal tubules.

References

Legare C.,et al.Endocrinology 140:3318-3327(1999).
Nakagawa J.,et al.J. Biol. Chem. 277:17883-17891(2002).
Xia X.Y.,et al.Zhonghua Nan Ke Xue 9:24-27(2003).
Huang C.,et al.Submitted (DEC-1998) to the EMBL/GenBank/DDBJ databases.
Liu Q.,et al.Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases.

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$ 395.00
Cat# ALS16198
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