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PON1 / ESA Antibody
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P |
|---|---|
| Primary Accession | P27169 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 40kDa |
| Dilution | IHC-P (10 µg/ml), WB (1:500-1:3000), |
| Gene ID | 5444 |
|---|---|
| Other Names | Serum paraoxonase/arylesterase 1, PON 1, 3.1.1.2, 3.1.1.81, 3.1.8.1, Aromatic esterase 1, A-esterase 1, K-45, Serum aryldialkylphosphatase 1, PON1, PON |
| Target/Specificity | Human PON1 |
| Reconstitution & Storage | Aliquot and freeze at -20° C. Avoid freeze-thaw cycles. |
| Precautions | PON1 / ESA Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PON1 |
|---|---|
| Synonyms | PON |
| Function | Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediates an enzymatic protection of low density lipoproteins against oxidative modification and the consequent series of events leading to atheroma formation. |
| Cellular Location | Secreted, extracellular space. |
| Tissue Location | Plasma, associated with HDL (at protein level). Expressed in liver, but not in heart, brain, placenta, lung, skeletal muscle, kidney or pancreas. |
| Volume | 50 µl |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediates an enzymatic protection of low density lipoproteins against oxidative modification and the consequent series of events leading to atheroma formation.
References
Hassett C.,et al.Biochemistry 30:10141-10149(1991).
Adkins S.,et al.Am. J. Hum. Genet. 52:598-608(1993).
La Du B.N.,et al.Chem. Biol. Interact. 87:25-34(1993).
Furlong C.E.,et al.Chem. Biol. Interact. 87:35-48(1993).
Clendenning J.B.,et al.Genomics 35:586-589(1996).
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