|Application ||WB, IHC-P, IF, ICC, IP|
|Reactivity||Human, Mouse, Rat, Hamster, Pig, Bovine, Guinea Pig, Dog|
|Dilution||IF (1:200), IHC-P (10 µg/ml), WB (1:5000)|
|Other Names||Heat shock protein beta-2, HspB2, DMPK-binding protein, MKBP, HSPB2|
|Target/Specificity||Detects a 25kD or 27kD protein corresponding to the molecular mass of hsp25/27 on SDS PAGE immunoblots.|
|Reconstitution & Storage||Store at -20°C.|
|Precautions||HSPB2 / HSP27 Antibody (clone 8A7) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May regulate the kinase DMPK.|
|Cellular Location||Cytoplasm. Nucleus. Note=Localizes to nuclear foci|
|Tissue Location||Expressed preferentially in skeletal muscle and heart but not in the lens|
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Provided below are standard protocols that you may find useful for product applications.
May regulate the kinase DMPK.
Iwaki A.,et al.Genomics 45:386-394(1997).
Suzuki A.,et al.J. Cell Biol. 140:1113-1124(1998).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Elisei R.,et al.J. Endocrinol. Invest. 16:533-540(1993).
Vos M.J.,et al.Biochim. Biophys. Acta 1793:1343-1353(2009).
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