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>   home   >   Products   >   Primary Antibodies   >   MED24 / TRAP100 Antibody (aa801-850)   

MED24 / TRAP100 Antibody (aa801-850)

Rabbit Polyclonal Antibody

     
  • WB - MED24 / TRAP100 Antibody (aa801-850) ALS16263
    Western blot of TRAP100 (K834) pAb in extracts from 293 cells.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC, IHC-P, IF
Primary Accession O75448
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 110kDa
Dilution IF (1:50-1:200), IHC (1:50-1:200), IHC-P (5 µg/ml), WB (1:500-1:1000) ,
Additional Information
Gene ID 9862
Other Names Mediator of RNA polymerase II transcription subunit 24, Activator-recruited cofactor 100 kDa component, ARC100, Cofactor required for Sp1 transcriptional activation subunit 4, CRSP complex subunit 4, Mediator complex subunit 24, Thyroid hormone receptor-associated protein 4, Thyroid hormone receptor-associated protein complex 100 kDa component, Trap100, hTRAP100, Vitamin D3 receptor-interacting protein complex 100 kDa component, DRIP100, MED24
Target/Specificity Human TRAP100 / MED24
Reconstitution & Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
PrecautionsMED24 / TRAP100 Antibody (aa801-850) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MED24
Function Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Cellular Location Nucleus.
Tissue Location Ubiquitous. Abundant in skeletal muscle, heart and placenta.
Volume 50 µl
Citations (0)

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Background

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

References

Yuan C.-X.,et al.Proc. Natl. Acad. Sci. U.S.A. 95:7939-7944(1998).
Rachez C.,et al.Genes Dev. 12:1787-1800(1998).
Nagase T.,et al.DNA Res. 2:167-174(1995).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Zody M.C.,et al.Nature 440:1045-1049(2006).

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$ 395.00
Cat# ALS16263
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