|Application ||WB, IHC-P, E|
|Reactivity||Human, Rabbit, Hamster, Pig, Horse, Xenopus, Bovine, Dog|
|Dilution||ELISA (1:64000), IHC-P (5 µg/ml), WB (0.3-1 µg/ml)|
|Other Names||Lamin-B1, LMNB1, LMN2, LMNB|
|Target/Specificity||Human LMNB1 / Lamin B1. This antibody is expected to recognize both reported isoforms (NP_005564.1; NP_001185486.1).|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||LMNB1 / Lamin B1 Antibody (aa526-537) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin.|
|Cellular Location||Nucleus inner membrane; Lipid-anchor; Nucleoplasmic side|
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Provided below are standard protocols that you may find useful for product applications.
Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin.
Pollard K.M.,et al.Mol. Cell. Biol. 10:2164-2175(1990).
Lin F.,et al.Genomics 27:230-236(1995).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Bienvenut W.V.,et al.Submitted (DEC-2008) to UniProtKB.
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