|Application ||WB, IHC-P, IF|
|Dilution||IF (1:100), IHC-P (10 µg/ml), WB (1:4000)|
|Other Names||Synaptophysin, Major synaptic vesicle protein p38, SYP|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||SYP / Synaptophysin Antibody (clone 4A2) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity (By similarity).|
|Cellular Location||Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Cell junction, synapse, synaptosome|
|Tissue Location||Characteristic of a type of small (30-80 nm) neurosecretory vesicles, including presynaptic vesicles, but also vesicles of various neuroendocrine cells of both neuronal and epithelial phenotype|
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Provided below are standard protocols that you may find useful for product applications.
Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity (By similarity).
Suedhof T.C.,et al.Nucleic Acids Res. 15:9607-9607(1987).
Oezcelik T.,et al.Am. J. Hum. Genet. 47:551-561(1990).
Fisher S.E.,et al.Genomics 45:340-347(1997).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Ross M.T.,et al.Nature 434:325-337(2005).
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