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GIMAP4 Antibody (clone 1C6)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, IF, FC |
|---|---|
| Primary Accession | Q9NUV9 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | 1C6 |
| Calculated MW | 38kDa |
| Dilution | Flo (1:100), IF (1:100), IHC-P (10 µg/ml), WB (1:2000) , |
| Gene ID | 55303 |
|---|---|
| Other Names | GTPase IMAP family member 4, Immunity-associated nucleotide 1 protein, IAN-1, hIAN1, Immunity-associated protein 4, GIMAP4, IAN1, IMAP4 |
| Target/Specificity | Human GIMAP4 |
| Reconstitution & Storage | Store at -20°C. Minimize freezing and thawing. |
| Precautions | GIMAP4 Antibody (clone 1C6) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GIMAP4 |
|---|---|
| Synonyms | IAN1, IMAP4 |
| Function | During thymocyte development, may play a role in the regulation of apoptosis (By similarity). GTPase which exhibits a higher affinity for GDP than for GTP. |
| Cellular Location | Cytoplasm, cytosol. |
| Tissue Location | Highly expressed in spleen and peripheral blood leukocytes that contain mostly T- and B-lymphocytes. Expressed specifically in resting T- and B-lymphocytes and expression significantly decreases during B- or T-lymphocyte activation. Expressed at lower levels in thymus, ovary, colon and small intestine |
| Volume | 50 µl |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
May play a role in regulating lymphocyte apoptosis (By similarity). Exhibits intrisinic GTPase activity. Shows a higher affinity for GDP over GTP (about 12-fold higher), and binding shows an absolute requirement for magnesium.
References
Cambot M.,et al.Blood 99:3293-3301(2002).
Liu Y.Q.,et al.Submitted (DEC-1998) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Schwefel D.,et al.Structure 21:550-559(2013).
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