|Application ||WB, IHC-P, IF, E|
|Dilution||IF (20 µg/ml), IHC-P (10 µg/ml), WB (1-2 µg/ml)|
|Other Names||Tyrosine-protein phosphatase non-receptor type 5, 188.8.131.52, Neural-specific protein-tyrosine phosphatase, Striatum-enriched protein-tyrosine phosphatase, STEP, PTPN5|
|Target/Specificity||PTPN5 antibody is human and mouse reactive.|
|Reconstitution & Storage||Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.|
|Precautions||PTPN5 / STEP Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May regulate the activity of several effector molecules involved in synaptic plasticity and neuronal cell survival, including MAPKs, Src family kinases and NMDA receptors.|
|Cellular Location||Endoplasmic reticulum membrane; Multi-pass membrane protein|
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May regulate the activity of several effector molecules involved in synaptic plasticity and neuronal cell survival, including MAPKs, Src family kinases and NMDA receptors.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Taylor T.D.,et al.Nature 440:497-500(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Li X.,et al.Genomics 28:442-449(1995).
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