|Application ||WB, IHC-P, ICC, IHC-Fr|
|Calculated MW||94574 Da|
|Dilution||IHC-Fr (1:100 - 1:200), IHC-P (10 µg/ml), WB (1:100 - 1:1000),|
|Other Names||NCAM1, CD56, CD56 antigen, MSK39, NCAM-1, N-CAM-1, NCAM|
|Target/Specificity||Recognizes an epitope in the NCAM exons 11-13 which is dependent on an intact conformation of the first fibronectin type-III homologous domain encoded by these exons. Stains NCAM which is present in small cell lung cancer and lung carcinoids. It also ...|
|Reconstitution & Storage||PBS containing 0.09% sodium azide. Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.|
|Precautions||NCAM / CD56 Antibody (clone 123C3) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc.|
|Cellular Location||Isoform 1: Cell membrane; Single-pass type I membrane protein Isoform 3: Cell membrane; Lipid-anchor, GPI- anchor Isoform 5: Secreted.|
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Provided below are standard protocols that you may find useful for product applications.
This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc.
Barton C.H.,et al.Development 104:165-173(1988).
Lanier L.L.,et al.J. Immunol. 146:4421-4426(1991).
Saito S.,et al.Lung Cancer 10:307-318(1994).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Totoki Y.,et al.Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
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